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Buy Vasoactive Intestinal Peptide VIP

Vasoactive Intestinal Peptide (VIP) is a neuropeptide that plays a key role in regulating smooth muscle activity, secretion of fluids, and blood flow in the gastrointestinal tract. It is primarily found in the gut, pancreas, and certain neurons throughout the body. VIP is significant in France medical research due to its potential in treating conditions like inflammatory bowel disease, asthma, and pulmonary hypertension.

Buy VIP Vasoactive Intestinal Peptide {name1} from PharmaGrade.Store

Vasoactive Intestinal Peptide France Products

At PharmaGrade.Store supplies high purity peptides to the France industry:

    • Vasoactive Intestinal Peptide Vial – White, lyphollized peptide for reconstitution using bacteriostatic water.
      Vasoactive Intestinal peptide France is available in 2mg vials.
    • Vasoactive Intestinal Peptide Nasal Spray – a convenient and painless way of administering peptides. The VIP Nasal spray is supplied ready to use. Choose from 15ml or 30ml nasal sprays here.
    • Vasoactive Intestinal Peptide Pre-Mixed Peptide Pen – Pre-mixed pen kits and refill cartridges come ready to use pre-mixed with VIP peptide and bacteriostatic water. Buy VIP 2mg Pre-Mixed Pen here.

 

Vasoactive Intestinal Peptide

France Clinical studies have found that Vasoactive Intestinal Peptide (VIP) exerts its effects by binding to two main receptors, VPAC1 and VPAC2, which are part of the G-protein coupled receptor family [1]. Once VIP attaches to these receptors, it activates intracellular signalling pathways, primarily through the stimulation of adenylyl cyclase. This leads to an increase in cyclic AMP (cAMP) levels, which serves as a secondary messenger to modulate various cellular functions [2].

Vasoactive Intestinal Peptide plays a critical role in relaxing smooth muscles, reducing inflammation, and regulating immune system responses. For example, it promotes vasodilation by stimulating the relaxation of vascular smooth muscle cells and increasing blood flow [3]. Additionally, it enhances secretion in the gastrointestinal tract by influencing electrolyte and water transport. Its anti-inflammatory effects stem from its ability to inhibit the release of pro-inflammatory cytokines.

Through these mechanisms, VIP’s role in regulating vital processes in the gastrointestinal, respiratory, and circulatory systems, underpinning its potential in therapeutic applications.

Potential Benefits of VIP Peptide

France Scientific studies have established the following potential benefits and applications of Vasoactive Intestinal Peptide France :

  • Reduces inflammation: by inhibiting the release of pro-inflammatory cytokines, VIP may aid conditions like inflammatory bowel disease and arthritis [4].
  • Promotes smooth muscle relaxation: thus helping in the treatment of asthma by improving airway dynamics and reducing bronchoconstriction [3].
  • Enhances vasodilation: By improving blood flow and potentially benefiting conditions like pulmonary hypertension and cardiac fibrosis [5].
  • Aids gut health – VIP regulates electrolyte and water balance in the gastrointestinal tract, offering relief for chronic diarrhoea or irritable bowel syndrome (IBS) [4].
  • Supports immune modulation: VIP may possibly reduce the severity of autoimmune diseases by regulating T-cell activity [6].
  • Improves gastrointestinal motility: this addresses disorders like gastroparesis by ensuring smooth muscle coordination [7].
  • Protects neurological health: by acting as a neuroprotective agent, VIP has shown promise in conditions like Parkinson’s and Alzheimer’s [8].
  • Promotes healing and cellular repair: this could contribute positively to tissue regeneration and injury recovery processes.
  • Potential anti-cancer properties: through its ability to modulate cell growth and apoptosis in certain tumour cells [9].

Vasoactive Intestinal Peptide France Research

Clinical research on the efficacy of Vasoactive Intestinal Peptide (VIP) has unveiled its promising therapeutic potential across various diseases. Studies show that VIP plays a pivotal role in reducing inflammation, making it a viable candidate for treating chronic conditions like inflammatory bowel disease and rheumatoid arthritis [4]. Its ability to relax airway smooth muscles has been explored in asthma therapies, with positive effects on reducing bronchoconstriction [3].

France Research also highlights its role in pulmonary hypertension by enhancing vasodilation and improving blood flow. Additionally, VIP demonstrates neuroprotective properties in conditions like Alzheimer’s and Parkinson’s disease [8]. Emerging evidence from a team of scientists suggests it may modulate tumour growth, pointing toward potential applications in cancer treatment [9].

VIP Specifications:

View PharmaGrade Store Vasoactive Intestinal Peptide France  HPLC Certificate here.

Sequence: HSDAVFTDNYXRLRKQMAVKKYLNSXLN

Molecular Formula:C147H237N43043S

Molecular Weight: Unknown

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Buy BPC-157 VIP Peptide Stack {name1} from PharmaGrade.Store

Buy BPC-157 VIP France Peptide Stack

BPC-157 & VIP Peptide Stack

Combining BPC-157 and Vasoactive Intestinal Peptide (VIP) peptides may enhance healing and tissue repair by leveraging their complementary mechanisms. While BPC-157 accelerates wound healing and promotes recovery of muscles, tendons, and the gastrointestinal tract, VIP reduces inflammation and enhances smooth muscle relaxation, improving overall recovery.

Together, they could provide synergistic benefits by simultaneously modulating immune responses and promoting cellular repair. This combination may also support better gastrointestinal health, reduced inflammation in chronic conditions, and improved functionality in patients with complex healing needs.

Frequently Asked Questions about Vasoactive Intestinal Peptide France

Is VIP Peptide approved for human consumption?

No, the short peptide hormone Vasoactive Intestine Peptide (VIP) is not currently approved for human consumption. It is primarily available for areas of research purposes and is often studied in laboratory or pharmacy settings to explore its potential therapeutic benefits. VIP has not been classified as a drug, food, nutrition or medicinal product by regulatory authorities like the FDA or public health, and its use in humans is restricted to clinical trials or research under professional supervision and with adherence to applicable laws.

How does VIP Peptide enhance the immune system?

VIP peptide improves immunity by modulating the immune system and reducing harmful inflammation. It interacts with immune cells, such as T-cells and macrophages, to regulate their activity and prevent excessive immune responses that can lead to tissue damage. VIP is known to suppress the production of pro-inflammatory cytokines while promoting anti-inflammatory cytokines, creating a balanced immune environment.

Additionally, VIP helps protect tissues from immune-related damage by reducing oxidative stress and supporting cellular repair processes. Its ability to regulate neuroinflammation also contributes to overall immune health, as the nervous and immune systems are closely interconnected. This makes VIP a promising candidate for managing autoimmune and inflammatory conditions.

 

Further Reading

Blogs:

This blog investigates VIP acting as a neurotransmitter, facilitating communication between neurons and influencing processes like inflammation control and neurotransmitter release. It protects neurons from oxidative stress and inflammation, while also enhancing the release of key neurotransmitters like acetylcholine, which supports memory and muscle control.

The article emphasizes VIP’s potential in treating neurological disorders and its broader impact on brain function and the central nervous system, making it a promising focus for future medical advancements.

The blog explores the connection between gut peptides and brain health, emphasizing their role in the gut-brain axis. It highlights how peptides like BPC-157 and VIP influence cognitive function, anxiety reduction, and overall brain vitality. BPC-157 is noted for its neuroprotective and regenerative properties, while VIP supports neurotransmission, inflammation modulation, and cerebral blood flow. The article underscores the therapeutic potential of these peptides in enhancing memory, focus, and emotional well-being, while also promoting neuroplasticity and long-term brain health.

Scientific Research:

[1] Couvineau A, Laburthe M. VPAC receptors: structure, molecular pharmacology and interaction with accessory proteins. Br J Pharmacol. 2012 May;166(1):42-50. 

[2] Moody TW, Jensen RT. Pituitary adenylate cyclase-activating polypeptide/vasoactive intestinal peptide [Part 1]: biology, pharmacology, and new insights into their cellular basis of action/signaling which are providing new therapeutic targets. Curr Opin Endocrinol Diabetes Obes. 2021 Apr 1;28(2):198-205.

[3] Delgado M, Ganea D. Vasoactive intestinal peptide: a neuropeptide with pleiotropic immune functions. Amino Acids. 2013 Jul;45(1):25-39.

[4] Sun X, Huang Y, Zhang YL, Qiao D, Dai YC. Research advances of vasoactive intestinal peptide in the pathogenesis of ulcerative colitis by regulating interleukin-10 expression in regulatory B cells. World J Gastroenterol. 2020 Dec 28;26(48):7593-7602.

[5] Wu D, Lee D, Sung YK. Prospect of vasoactive intestinal peptide therapy for COPD/PAH and asthma: a review. Respir Res. 2011 Apr 11;12(1):45.

[6] Martínez C, Juarranz Y, Gutiérrez-Cañas I, Carrión M, Pérez-García S, Villanueva-Romero R, Castro D, Lamana A, Mellado M, González-Álvaro I, Gomariz RP. A Clinical Approach for the Use of VIP Axis in Inflammatory and Autoimmune Diseases. Int J Mol Sci. 2019 Dec 20;21(1):65.

[7] Eklund S, Jodal M, Lundgren O, Sjöqvist A. Effects of vasoactive intestinal polypeptide on blood flow, motility and fluid transport in the gastrointestinal tract of the cat. Acta Physiol Scand. 1979 Apr;105(4):461-8.

[8] Korkmaz OT, Ay H, Aytan N, Carreras I, Kowall NW, Dedeoglu A, Tuncel N. Vasoactive Intestinal Peptide Decreases β-Amyloid Accumulation and Prevents Brain Atrophy in the 5xFAD Mouse Model of Alzheimer’s Disease. J Mol Neurosci. 2019 Jul;68(3):389-396.

[9] Hara M, Takeba Y, Iiri T, Ohta Y, Ootaki M, Watanabe M, Watanabe D, Koizumi S, Otsubo T, Matsumoto N. Vasoactive intestinal peptide increases apoptosis of hepatocellular carcinoma by inhibiting the cAMP/Bcl-xL pathway. Cancer Sci. 2019 Jan;110(1):235-244. 

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